Found 61 matching trials
A Placebo-Controlled, Phase I, Pilot Clinical Trial to Evaluate the Safety and Immunogenicity of ENV 2-3, a Yeast-Derived Recombinant Envelope Protein of Human Immunodeficiency Virus-1, in Combination With MTP-PE/MF59 in Individuals With HIV Infection (Placebo Patients Receive MF59 Emulsion Only) PHASE1 To determine the safety and immunogenicity of Env 2-3 in combination with M...
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Univ. of Rochester AVEG
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Evaluating the Safety and Immunogenicity of Polyvalent DNA/gp120 HIV Vaccine in Healthy, HIV-uninfected Adults PHASE1 The purpose of the study is to evaluate the safety, tolerability, and immun...
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Brigham and Women's Hospital
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Safety and Immunogenicity of Clade C ALVAC and gp120 HIV Vaccine PHASE1 The purpose of this study is to evaluate the safety and immune response to ...
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Polana Canico Health Research and Training Center (CISPOC), National Institute of Health (INS) CRS
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Modelling the Interaction Between Rationally-designed Synthetic Model Viral Protein Immunogens PHASE1 The objective of this experimental medicine study is to determine the exten...
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NIHR Imperial Clinical Resarch Facility
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Combining TLR9 Agonist With bNAbs for Reservoir Reduction and Immunological Control of HIV PHASE2 This study is designed to evaluate the safety and efficacy of lefitolimod a...
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Dept. of Internal Medicine, University of Utah
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Assessing the HERV-W Env ANtagonist GNbAC1 for Evaluation in an Open Label Long-term Safety Study in Patients With Multiple Sclerosis PHASE2 The humanised IgG4 monoclonal antibody GNbAC1 targets the envelope protein ...
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Dose, Safety, Tolerability, and Immunogenicity of an HIV-1 Vaccine, VRC-HIVRGP096-00-VP, With Alum in Healthy Adults PHASE1 Background:
HIV stands for human immunodeficiency virus, which is the viru...
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National Institutes of Health Clinical Center
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Evaluating the Safety and Immunogenicity of HIV-1 BG505 SOSIP.664 gp140 With TLR Agonist and/or Alum Adjuvants in Healthy, HIV-uninfected Adults PHASE1 The purpose of this study is to evaluate the safety and immunogenicity of H...
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Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of 16055 NFL Delta Gly4 Env Protein Trimer and Trimer 4571 Combined With 3M-052-AF + Alum Adjuvant and Ad4-Env145NFL Viral Particles as Heterologous Prime-boost Regimens in Adult Participants Without HIV. PHASE1 The goal of this clinical trial is to test 16055 NFL delta Gly4 Env protein...
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Active Not Recruiting
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A Combination Efficacy Study in Africa of Two DNA-MVA-Env Protein or DNA-Env Protein HIV-1 Vaccine Regimens With PrEP PHASE2 This international, multi-centre, double-blind vaccine study is a three-arm...
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MRC/UVRI and LSHTM Uganda Research Unit
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